What is Spironolactone?

Spironolactone is a medication that may be used in patients with heart failure or kidney conditions. It helps to decrease the amount of extra salad and water in the body by increasing the amount of urine it makes. It belongs to a class of medications called diuretics or “water pills” but is a special type as it stops potassium being lost in the urine.

How do I give this medication?

Spironolactone comes in tablet and liquid (suspension form). Liquid forms should be shaken well before being given. It is given one to two times a day. 

The dosage is computed according to the weight of your child. Kindly refer to your prescription for the correct dosage.

How is this medication stored?

• Store liquid in the refrigerator.
• Keep tablets at room temperature and away from sunlight.
• Keep tablets away from moist or damp places.
• Keep medication out of the reach of small children.

What should I do if a dose is missed?

Give the missed dose as soon as you remember. But if it is close to the time for the next dose, skip the missed dose–give the next dose at the normal time.

Do not double up the dose.

If your child vomits within 15 minutes after a dose–give a new dose. If longer than 15 minutes, then wait until the next normal medication time.

Possible common side effects

• Stomach upset
• Diarrhea (loose, watery stools)
• Thirsty, dry mouth
• Headache

When to seek care

• Skin rash 
• Poor appetite
• Drowsiness or lethargy (excess weakness or tiredness)
• Any new symptoms that seem different from your usual heart symptoms

Other notes or special instructions:

• If the child has taken or been given an extra dose and you are worried, call Healthlink BC at 811
• If your child accidentally has taken or been given an overdose, call:

BC Drug and Poison Centre:

1-800-567-8911 or 604-682-5050

• This medication can lower blood pressure. Ask your child to get out of bed or stand up slowly.
• This medicine may cause the body to gain potassium. Spironolactone is often given with another diuretic called furosemide to work against the potassium loss. Your doctor may order bloodwork to check sodium and potassium levels.
• Don’t give your child any potassium supplements, unless prescribed by your doctor, or too many foods that are high in potassium such as bananas or orange juice.
• Hold the dose if your child is not eating or drinking well.
• Check with your doctor or pharmacist before starting any new medications, over the counter medications, and herbal products.
• Spironolactone liquid must be made by a specialized pharmacy. Check with your pharmacy to make sure they can make spironolactone for your child.
• Check the expiry date of the liquid.